Thursday 25 February 2016

INTERMEDIARY METABOLISM

III B.Sc., SEMESTER V MAJOR CORE 9: INTERMEDIARY METABOLISM (METABOLIC DISORDERS NOT INCLUDED)

Unit I
METABOLISM OF CARBOHYDRATES
Glycogenesis
Glycogenolysis
Glycolysis
Citric acid cycle
Glyoxylate cycle
Gluconeogenesis
HMP shunt pathway
Uronic acid pathway.

Unit II
METABOLISM OF LIPIDS & STEROIDS
Biosynthesis of fatty acids and some important phospholipids
Biosynthesis of fatty acids and some important phospholipids
Degradation of fats
beta oxidation of saturated and unsaturated fatty acids
beta oxidation of saturated and unsaturated fatty acids
degradation of phospholipids
Metabolism of ketone bodies
Steroids – Biosynthesis and degradation of cholesterol

Unit III
AMINOACID METABOLISM
Amino acid pool
Oxidative and non oxidative deamination
Oxidative and non oxidative deamination
transamination
transmethylation.
Urea cycle
Creatinine formation
Outline of various amino acid metabolism.
Metabolism of essential amino acids
Phenyl alanine and tyrosine
tryptophan
branched chain aminoacids
sulphur containing aminoacids.

Unit IV
METABOLISM OF NUCLEIC ACIDS
Biosynthesis (denova and salvage pathway) of purines and pyrimidines
Catabolism of purines and pyrimidines
Detoxication mechanisms – conjugation
Detoxication mechanisms hydrolysis
Detoxication mechanisms reduction & Oxidation

Unit V
REDOX SYSTEMS OF MITOCHONDRIA AND CHLOROPLAST
Respiratory chain
Functions of NAD+ , NADP+
Functions of FMN, FAD
cytochrome
CoQ in hydrogen transfer
Formation of ATP
High energy compounds and linkages
Photosynthesis - light reactions and dark reactions.